List of Tests Currently Provided by PGx Lab
| name | description | ||
|---|---|---|---|
| 5-HTT | Serotonin transporter
5'UTR 44bp insertion/deletion long allele (wild-type) short allele |
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| CYP 1A2 | Cytochrome P450 1A2
2 promoter sequence variants CYP1A2*1C (-3860 G>A) CYP1A2*1F (-163 C>A) |
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| CYP 2C19 | Cytochrome P450 2C19
7 coding sequence variants CYP2C19*2 CYP2C19*3 CYP2C19*4 CYP2C19*5 CYP2C19*6 CYP2C19*7 CYP2C19*8 |
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| CYP 2C9 | Cytochrome P450 2C9
5 coding sequence variants CYP2C9*2 CYP2C9*3 CYP2C9*4 CYP2C9*5 CYP2C9*6 |
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| CYP 2D6 | Cytochrome P450 2D6
12 coding sequence variants 2 copy number variants CYP2D6*2 CYP2D6*3 CYP2D6*4 CYP2D6*5 (deletion) CYP2D6*6 CYP2D6*7 CYP2D6*8 CYP2D6*9 CYP2D6*10 CYP2D6*11 CYP2D6*12 CYP2D6*17 CYP2D6*Dup (duplication) |
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| CYP2C9-VKORC1 Combo | Cytochrome P450 2C9:
5 coding sequence variants CYP2C9*2 CYP2C9*3 CYP2C9*4 CYP2C9*5 CYP2C9*6 VKORC1: 1 promoter sequence variant -1639 G>A 6 coding sequence variants 85 G>T 121 G>T 134 T>C 172 A>G 1331 G>A 3487 T>G |
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| DNA isolation | DNA isolated from mammalian tissue (including human)
Concentration and quality assessed upon request. |
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| Factor II (Prothrombin) | Factor II (Prothrombin)
3' UTR sequence variant 20210 G>A |
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| Factor V Leiden | Factor V
1 coding sequence variant 1691 G>A |
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| HTR | Serotonin Receptor SNPs
2A gene: 74C>A, 102T>C, 1354C>T 2C gene: -759 C>T, 796 G>C |
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| Miscellaneous send out | Test referred to LabCorp | ||
| MPA serum | Mycophenolic Acid - an immunosuppressant | ||
| MPA-G serum | Mycophenolic acid-glucuronide
Metabolite of MPA, may accumulate in transplant patients with poor renal function. Can only be ordered together with MPA |
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| MTHFR | Methylenetetrahydrofolate Reductase
2 coding sequence variants MTHFR 677 C>T MTHFR 1298 A>C |
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| NAT2 | N-Acetyltransferase 2
7 coding sequence variants defining 26 different haplotypes 191 G>A (*14 alleles) 282 C>T 341 T>C (*5 alleles) 481 C>T 590 G>A (*6 alleles) 803 A>G 857 G>A (*7 alleles) |
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| Promotional test | |||
| STAT (RUSH orders) | STAT/RUSH turn-around
$50 fee 3 days for blood samples 5 days for buccal samples |
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| VKORC1 | 1 promoter sequence variant
-1639 G>A |
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